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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP8A1 All Species: 24.24
Human Site: Y626 Identified Species: 44.44
UniProt: Q9Y2Q0 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2Q0 NP_006086.1 1164 131369 Y626 F Q E W R A V Y Q R A S T S V
Chimpanzee Pan troglodytes XP_001150768 1164 131363 Y626 F Q E W R A V Y Q R A S T S V
Rhesus Macaque Macaca mulatta XP_001099138 1164 131392 Y626 F Q E W R A V Y Q R A S T S V
Dog Lupus familis XP_849357 1158 131123 A623 W R A V Y Q R A S T S V Q N R
Cat Felis silvestris
Mouse Mus musculus P70704 1149 129748 Y611 F E E W R A V Y H R A S T S V
Rat Rattus norvegicus XP_223390 1134 128100 A600 L K H L E Q F A T E G L R T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518853 932 104820 N403 R A A A A V Q N R A L K L E E
Chicken Gallus gallus XP_420729 1223 137907 Y685 Y Q E W L D V Y H R A S T A I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002666697 916 102033 I387 A Y N L L T F I I L Y N N L I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137649 1324 149578 F787 Y Q E W S Q T F D K A S V A L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200260 1167 132097 Y613 Y E D W S A T Y Y K A S T A I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9XIE6 1213 137734 F649 Y D S W N E K F I Q A K S A L
Baker's Yeast Sacchar. cerevisiae P39524 1355 153826 Y776 Y E E W N S I Y N E A A T T L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.8 96.9 N.A. 95.8 94.5 N.A. 74.4 88.5 N.A. 53.8 N.A. 50.9 N.A. N.A. 57.6
Protein Similarity: 100 100 100 98 N.A. 97.7 96.3 N.A. 76.9 92.4 N.A. 63.4 N.A. 65.4 N.A. N.A. 74.8
P-Site Identity: 100 100 100 0 N.A. 86.6 0 N.A. 0 60 N.A. 0 N.A. 33.3 N.A. N.A. 40
P-Site Similarity: 100 100 100 26.6 N.A. 93.3 20 N.A. 6.6 80 N.A. 13.3 N.A. 66.6 N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 39.2 39.9 N.A.
Protein Similarity: N.A. N.A. N.A. 58.6 57.6 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 16 8 8 39 0 16 0 8 70 8 0 31 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 0 0 8 0 0 8 0 0 0 0 0 0 % D
% Glu: 0 24 54 0 8 8 0 0 0 16 0 0 0 8 8 % E
% Phe: 31 0 0 0 0 0 16 16 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % G
% His: 0 0 8 0 0 0 0 0 16 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 8 16 0 0 0 0 0 24 % I
% Lys: 0 8 0 0 0 0 8 0 0 16 0 16 0 0 0 % K
% Leu: 8 0 0 16 16 0 0 0 0 8 8 8 8 8 31 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 16 0 0 8 8 0 0 8 8 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 39 0 0 0 24 8 0 24 8 0 0 8 0 0 % Q
% Arg: 8 8 0 0 31 0 8 0 8 39 0 0 8 0 8 % R
% Ser: 0 0 8 0 16 8 0 0 8 0 8 54 8 31 0 % S
% Thr: 0 0 0 0 0 8 16 0 8 8 0 0 54 16 0 % T
% Val: 0 0 0 8 0 8 39 0 0 0 0 8 8 0 31 % V
% Trp: 8 0 0 70 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 39 8 0 0 8 0 0 54 8 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _